Two injections a year for high blood pressure: what the news really means
Recent studies suggest that in the future, some people with high blood pressure may be able to control it with just two injections per year instead of daily tablets.
However, this treatment is still under clinical trials and is not yet available for regular use.
What is this new injection?
One of the most advanced drugs being studied is called zilebesiran.
How it works
- It uses a modern technology called RNA interference (siRNA).
- It blocks the liver from producing angiotensinogen, a protein that increases blood pressure.
- When this protein is reduced, blood vessels relax and pressure goes down.
How long does one injection work?
- Early studies show one injection can control blood pressure for up to 6 months.
- That means only two injections per year may be enough.
Some trials showed:
- Blood pressure dropped by about 10–15 mmHg after a single injection.
Why is this important?
Many people:
- Forget to take daily medicines
- Stop medicines after feeling better
- Need multiple tablets
Researchers say long-acting injections could:
- Keep blood pressure stable for months
- Reduce heart attack and stroke risk
- Make treatment easier for patients
Is it available now?
No. Not yet.
- The drug is still in Phase 3 clinical trials.
- Doctors are waiting for:
- Long-term safety results
- Proof that it reduces heart attacks and strokes
- It may take a few years before approval and availability.
Simple conclusion
- The idea of two injections a year for BP is real and promising.
- But it is still experimental.
- For now, daily medicines remain the standard treatment.
